Psilocybin Promotes Neuroplasticity through 5-HT2A Receptor agonism: Implications for Treatment of Depression

Brianna Peacock Introduction. Depression is a state of low mood with a lifetime prevalence of about 20% globally.1 Potential etiologies include the monoamine hypothesis which describes a decrease in molecules like serotonin.1,2 Loss or alteration of neuroplasticity may also play a role in pathogenesis, as suggested by the decreased BDNF…
Featured Abstracts Neuroscience Psychiatry

Fecal Microbiota Transplant Modulates Clostridium Clusters XIVa, IV, and Caudovirales Bacteriophages to Induce Remission in Ulcerative Colitis Patients

Adam Saleh Introduction: Ulcerative Colitis (UC) is a chronic idiopathic inflammatory disorder of the colon with continuous inflammation beginning in the rectum and ascending proximally. The disease can present clinically with varying severity of diarrhea and blood in stool, urgency, and tenesmus1. The pathogenesis of UC likely has contributions from…
Gastroenterology Microbiology

Minimally Invasive Preimplantation Genetic Testing for Aneuploidy in In vitro Fertilization

Natalie Miroballi Introduction. Infertile individuals often seek assisted reproductive technology (ART) to aid in conception, the most common of which is In vitro fertilization (IVF) therapy. The success rate of IVF is highly variable and depend on several clinical factors including the underlying causes of infertility and the woman’s age.…
Featured Abstracts Gynecology Reproduction

A Novel Approach to Non-Invasively Diagnosing Acute Compartment Syndrome of the Leg with Near-Infrared Spectroscopy

Austin Hagen Introduction. Patients with trauma to the lower leg may develop Acute Compartment Syndrome (ACS). Prompt diagnosis of ACS is critical to ensuring these patients receive fasciotomy to avoid complications such as paralysis.1 Clinical Signs of ACS alone have poor sensitivity and specificity, may be unattainable in obtunded patients,…
Engineering Medicine Neuroscience Orthopedics

Using Deferoxamine to Improve Soft Tissue Regeneration following Achilles Tendon Repair

Will Singer Introduction. The Achilles tendon is the strongest tendon in the body and facilitates walking, running, and jumping movements.1 Despite its strength, the incidence of Achilles tear has reached approximately 8.3 ruptures per 100,000 people over the last several years due to increased participation in recreational activities.2 Surgical management…
Featured Abstracts Orthopedics Wound Healing

Utilization of Machine Learning/Artificial Intelligence-Assisted Neuroimaging to Direct Treatment and Predict Outcomes in Ischemic Stroke

Caleb Haeussler Introduction. Ischemic stroke is a leading cause of morbidity and mortality in the United States, with an incidence of 700,000 ischemic strokes per year and 4 million stroke survivors.1,2 Ischemic stroke is a result of decreased blood flow to the brain, usually as result of thrombosis, embolism, or…
Cardiology Engineering Medicine Neuroscience