The Role of Micro-RNAs in Glioblastoma Biology

Kishore Balasubramanian Introduction. Glioblastoma multiforme (GBM) is one of the most common and fatal primary brain tumors. It is characterized by aggressive proliferation and motility and is highly resistant to conventional radiation and chemotherapy. Research into the dynamic interaction between microenvironment and the biological mechanisms specific to GBM cancer cells…
Cancer Featured Abstracts

SARS-CoV-2 in Pregnancy and the Inflammatory Response of IL-6 on Intrauterine Development of the Brain

Elaine Avshman Purpose. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious and infectious disease that has rapidly spread worldwide.1 As of September 2021, more than 125,000 cases of SARS-CoV-2 have been reported in pregnant women.1 Pregnant women are more likely to develop severe symptoms, as they are prone…
Featured Abstracts Inflammation Microbiology Neuroscience

The Role of Polycystin 1 and Polycystin 2 (PC1/PC2) in Calcium Intake and Pathogenesis of Autosomal Dominant Kidney Disease

Tarek Dawamne Introduction. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common potentially lethal single gene disorder. ADPKD is often associated with renal cysts that cause increased kidney malfunction such as hematuria, flank pain, kidney stones, carcinoma, in addition to other cardiovascular abnormalities1.  Methods. Many sources were reviewed to…
Featured Abstracts Renal Genitourinary

Psilocybin Promotes Neuroplasticity through 5-HT2A Receptor agonism: Implications for Treatment of Depression

Brianna Peacock Introduction. Depression is a state of low mood with a lifetime prevalence of about 20% globally.1 Potential etiologies include the monoamine hypothesis which describes a decrease in molecules like serotonin.1,2 Loss or alteration of neuroplasticity may also play a role in pathogenesis, as suggested by the decreased BDNF…
Featured Abstracts Neuroscience Psychiatry

Minimally Invasive Preimplantation Genetic Testing for Aneuploidy in In vitro Fertilization

Natalie Miroballi Introduction. Infertile individuals often seek assisted reproductive technology (ART) to aid in conception, the most common of which is In vitro fertilization (IVF) therapy. The success rate of IVF is highly variable and depend on several clinical factors including the underlying causes of infertility and the woman’s age.…
Featured Abstracts Gynecology Reproduction

Using Deferoxamine to Improve Soft Tissue Regeneration following Achilles Tendon Repair

Will Singer Introduction. The Achilles tendon is the strongest tendon in the body and facilitates walking, running, and jumping movements.1 Despite its strength, the incidence of Achilles tear has reached approximately 8.3 ruptures per 100,000 people over the last several years due to increased participation in recreational activities.2 Surgical management…
Featured Abstracts Orthopedics Wound Healing

Gut Dysbiosis in Type 1 Diabetes: Islet Cell Cytokine Response to Co-Culture with Bacteroides Dorei

Tanner Walker Introduction. Type 1 diabetes (T1D) is a chronic autoimmune disease, affecting 1.6 million Americans, that destroys β cells in the pancreas resulting in chronic hyperglycemia if left untreated with daily exogenous insulin 1 – 4. With 64,000 Americans being newly diagnosed each year, a juvenile onset, and a…
Endocrinology Featured Abstracts Microbiology