The Role of TIGIT as a Checkpoint for Cytotoxic Effector Cells in Melanoma Immunotherapy
Jennifer Bryan Introduction. Despite prevention and early detection efforts, melanoma incident rates, mortality, and morbidity remain high.1 One method of treatment is immunotherapy, which stimulates the body’s own immune system to defend against cancer. An important component to that immune response is cytotoxic effector cells, including natural killer (NK) and…