Inhibition of Kinase-Mediated Tau Hyperphosphorylation as a Therapeutic Target For Patients with Alzheimer’s Disease

Darshan Patel  Introduction. Alzheimer’s Disease (AD) is a chronic neurodegenerative disorder involving atrophy of the cerebral cortex1,2. Patients initially present clinically with prior onset dementia that typically leads to severe memory less and other cognitive deficits3. Past studies characterized Alzheimer’s Disease pathology by the accumulation of tau protein neurofibrillary tangles…
Neuroscience