Steven Maxwell – Proceedings of the Texas A&M Medical Student Grand Rounds

Lymphangiogenesis as a potential treatment target for myocardial injury

November 7, 2023 Barna Veli

Barna Veli Background In the United States, cardiovascular disease including myocardial infarction (MI) accounts for 40% of total deaths. MI accounts for 16.5% of all deaths from cardiovascular disease.1 After hospital discharge for MI, 13% of patients are diagnosed with heart failure within 30 days and 20-30% of patients are…

Cardiology

Inhibition of the Mannose Binding Lectin Pathways Creates Neuroprotective effect in Traumatic Brain Injury Induced Animal Models

November 7, 2023 Madison Demmer

Madison Demmer Introduction: Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide. 1.7 million people in the United States are afflicted by TBI annually.1 Immune response to a TBI consists of a Primary and Secondary response. Secondary insult can also include breakdown of the…

Neuroscience

The Role of CDK4/6 Inhibitor Combination Treatments in ER+ Breast Cancer

November 7, 2023 Megan Foster

Megan Foster Background: There are over 200,000 cases of BC diagnosed a year in the US, and for a woman, there is a 1/8 chance of being diagnosed with breast cancer in their lifetime. ER+ (Estrogen Receptor positive) breast cancer can be fairly common among women, as it is the…

Cancer

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September 25, 2023 Steven Maxwell

Uncategorized

Somatodendritic 5-HT1A Autoreceptor Desensitization due to Selective Serotonin Reuptake Inhibitor (SSRI) Therapy for Depression

September 16, 2023 Mathew Pietz

Mathew Pietz Introduction: Depression is a mood disorder and is highly prevalent in the United States. Mood disorders affect about 20% of the population while major depressive disorder (MDD) specifically affects almost 7% of the US population.2 Common symptoms of depression include insomnia, lethargy, unexplained pain, GI symptoms, and headaches.3…

Neuroscience Psychiatry

The Role of GABA in Alcohol Use Disorders

September 7, 2023 Steven Maxwell

Minhal Zaidi Alcohol use disorders are a result of heightened pleasure from repeated alcohol drinking behavior. 6 There are genetic components and environmental factors linked to alcohol use disorder. There is genetic heterogeneity in the risk of developing alcohol dependence, with different genetic loci contributing to the risk. 6 The…

Neuroscience

Leveraging Dysfunctional Mechanisms in Familial Hypertrophic Cardiomyopathy for Therapeutic Use in Patients with MyBPC Truncation Mutations

September 5, 2023 Kieran Paddock

Kieran Paddock Introduction: Familial hypertrophic cardiomyopathy (HCM) is a genetic disease characterized by hypertrophy of the ventricular wall, causing obstruction of the left ventricular outflow tract (LVOT).1–3 It is the most common cause of sudden cardiac death in athletes.2 It is predominantly due to mutations in MYBPC3 for myosin binding…

Cardiology

The Role of the mTOR Pathway in Treating Spinal Cord Injury for Neuron Survival and Axonal Growth

August 3, 2023 Zane Ahlfinger

Zane Ahlfinger Background: Spinal cord injury (SCI) is a “destructive neurological and pathological state that causes major motor, sensory, and autonomic dysfunctions”.1 Primary spinal cord injury is caused by direct blunt trauma to the spinal cord either from direct force or by impingement from vertebral fragments. Primary injury will most…

Neuroscience

A Discussion on the Evolution and Future of Healthcare Coverage: Debunking the Myths of Universal Healthcare

July 25, 2023 Tristen Slamowitz

Tristen Slamowitz Background: Healthcare coverage is defined as a means for financing a person’s healthcare expenses and is intended to reduce barriers to access, protect individuals from unexpected costs, and promote economic instability. In 2021, 8.3% of people living in the United States, or 27.2 million people, did not have…

Engineering Medicine Healthcare

Pilomyxoid Astrocytoma: Diagnostics and Targeted Therapy

July 25, 2023 Nicholas Panzo

Nicholas Panzo Background: Pilomyxoid astrocytoma (PMA) is a rare, aggressive variant of pilocytic astrocytoma (PA) which is associated with shorter progression-free and overall survival than PA.1 PMA tends to affect infants and younger children and has a higher probability of local recurrence and cerebrospinal spread than PA. 2, 3 There…

Cancer Engineering Medicine