Evaluating Genomic Methods for Assessing Fecal Microbiota Transplant (FMT) Efficacy After Antibiotic Use

Abhinaya Muruganandham Background.  Fecal microbiota transplantation (FMT) is a transformative therapy for restoring gut microbial ecology, particularly in treating recurrent Clostridioides difficile infection (rCDI) [1,2,3,4]. While highly successful for rCDI, its efficacy varies in other conditions like inflammatory bowel disease (IBD) or antibiotic-associated diarrhea [4]. Antibiotics significantly disrupt intestinal ecology,…
Engineering Medicine Featured Abstracts Microbiome

Bioelectronic Systems for Advanced Wound Management: Integrating Monitoring, Direct Therapy, and Closed-Loop Control

Maansi Srinivasan Background.  Chronic wounds represent a global health burden, affecting 1-2% of the population, including up to 40% of hospital beds in settings[1]. In the United States alone, approximately 8.5 million individuals are affected, with annual treatment costs exceeding $28 billion [1,2].  While most acute wounds follow a well-orchestrated…
Engineering Medicine Featured Abstracts Wound Healing

Resistance Training as a Therapeutic Intervention: Examining the Effects of Resistance Training on Common Chronic Diagnoses

Jenna Krueger Background:  Diabetes mellitus and hypertension are highly prevalent in the United States, affecting around 31.6% and 12.5% of adults, respectively, and contributing significantly to cardiovascular disease. Resistance training has gained attention as an effective nonpharmacologic intervention; however, variability exists in the literature regarding its comparative benefits and optimal…
Engineering Medicine Exercise Featured Abstracts

Contact Lens Risk Behaviors and Treatment Response in Acanthamoeba Keratitis

Tan Charmaine Background: Acanthamoeba keratitis (AK) is a rare, vision-threatening corneal infection caused by free-living Acanthamoeba species found in environmental sources such as water and soil1,2. It predominantly affects contact lens wearers, particularly those using soft lenses1,2. Following infection, organisms form drug-resistant cysts, contributing to prolonged and difficult treatment courses1,2,5.…
Engineering Medicine Featured Abstracts Ophthalmology

Prehospital Blood Product Transfusion in Traumatic Hypovolemic Shock: Advantages Over Crystalloid Resuscitation and Implications for Rural Trauma Care

Aaron Spearman Background: Traumatic hypovolemic shock remains a major cause of preventable early death after injury, and prehospital resuscitation strategy can significantly affect survival1. Recent trauma literature has moved away from large-volume crystalloid resuscitation because crystalloids do not restore oxygen-carrying capacity or coagulation factors and may worsen dilutional coagulopathy1. In…
Cardiology Engineering Medicine Featured Abstracts

Stem-Cell Derived: Extracellular Vesicles as a Novel Therapeutic for Alzheimer’s Disease

Nidhi Shah Background: Alzheimer’s disease (AD) is a complex, multifactorial neurodegenerative disorder driven by aging, genetic predispositions, and systemic molecular dysregulation.4 The traditional pathogenic model highlights the extracellular deposition of amyloid-beta (Aβ) plaques and intracellular hyperphosphorylated tau tangles.4,5 However, disease progression also involves chronic neuroinflammation mediated by microglia and severe…
Neuroscience Stem Cells

m6A RNA Modification in Cardiac Remodeling and Heart Failure

Priya Modi Background: Heart failure (HF) is a chronic progressive syndrome affecting more than six million adults in the United States and is associated with significant morbidity, mortality, and healthcare costs.¹ Current guideline-directed medical therapies improve survival by targeting neurohormonal pathways but do not directly address the underlying molecular drivers…
Cardiology Featured Abstracts

Targeting the NLRP3 Inflammasome for Neuroprotection in Traumatic Spinal Cord Injury

Daniyaal Qazi  Background: Traumatic spinal cord injury (SCI) is a major cause of permanent neurological disability, affecting approximately 20.6 million individuals globally as of 2019, with an annual incidence of 0.9 million new cases.1 The primary mechanical insult triggers a progressive secondary injury cascade leading to ischemia, glutamate excitotoxicity, oxidative…
Featured Abstracts Inflammation Neuroscience