Eun Yoon Introduction. Cardiovascular diseases represent the leading cause of mortality in Western countries.1 Vascular endothelial injury may lead to the development of atherosclerosis. An immediate restoration of vascular endothelial lining is critical for the prevention of atherosclerotic vascular diseases.2,3 […]
Shohaib Virani Introduction. Vascular disease is a broad array of disorders, including atherosclerosis, peripheral artery disease, aneurysms and blood clotting disorders, which can ultimately be tied to a damaged endothelium2. Vascular disease is associated with currently associated with old age, […]
Neha Ali Introduction. Cardiovascular disease is the leading cause of mortality in men and women in the USA. However, the risk of developing CV disease increases among women following menopause5. With increasing life expectancy, women may spend more than three […]
Jonathan Pirruccello Introduction: Cardiovascular disease is the leading cause of mortality in the United States.1 The major risk factor for cardiovascular disease is elevated blood cholesterol, most notably low-density-lipoprotein cholesterol (LDL-C).1,2 Statins are the current first-line therapy for hyperlipidemic patients, […]
Diem Q. Ngo Introduction. Cardiac remodeling is any structural changes in size, shape, and structure of the heart in response to increase cardiac stress. Cardiac remodeling can be seen in pathological conditions (e.g. heart failure) and show distinct characteristics such […]
Christopher Morin Introduction: Development of myocardial infarction (MI) occurs when a maturing plaque fissures and exposes its lipid rich core to components of circulating blood. The process ends with formation of an acute thrombus over the plaque with closure of […]
Melanie Kwan Introduction: Survival of cardiac stem cells (CSCs) after transplantation is necessary to facilitate cardiac repair following damage to the heart due to their potential ability to regenerate cardiomyocytes. The current best estimate of post-transplantation survival of CSCs is […]
Jonathan Knott Introduction: Hypertension remains one of the most important preventable causes of mortality world-wide. (1) It is estimated that more than 40% of persons greater than 25 years old have hypertension. The damage caused by long standing, uncontrolled hypertension […]
Ann Marie Karam Introduction: Heart Failure (HF) contributes to 1 in 8 deaths in America, with a risk of 1 in 5 of developing HF in one’s lifetime. In addition, HF can be difficult to diagnose, especially since most patients […]
Brittney Jackson Introduction: Cardiovascular diseases (CVD) are the leading cause of death in the United States and consume a significant amount of healthcare expenditures8. It is well researched and known that gene expression patterns are substantially altered in cardiac hypertrophy, […]