Category: Featured Abstracts

What’s “Bugging” You? – Investigating the Potential Role of the GI Microbiome in the Association between Appendectomy and Glucose Intolerance

July 25, 2023 Maya Pimentel
Maya Pimentel Background: Approximately 462 million people live with type 2 diabetes mellitus (T2D) worldwide.1 Although, once diagnosed, T2D is a lifelong, often progressive illness that requires regular medical evaluation, it is often a preventable condition. Therefore, attention has switched from a prophylactic response to a preventive approach in T2D…
Engineering Medicine Featured Abstracts Gastroenterology Microbiology

The Role of Antiphospholipid Antibodies in Miscarriage

July 24, 2023 Varshni Nandakumar
Varshni Nandakumar Background: Miscarriages are defined as the spontaneous loss of a pregnancy before 20 weeks of gestation and affect around 10% of all clinically-recognized pregnancies in the USA1. Moreover, there is a clear link between autoimmune conditions and higher incidences of miscarriage. Patients with autoimmune conditions can develop antiphospholipid…
Engineering Medicine Featured Abstracts Gynecology Reproduction

Focused Ultrasound Mediated Gene Therapy Delivery for the Treatment of Parkinson’s Disease

July 24, 2023 Isuru Somawardana
Isuru Somawardana Background: Parkinson’s disease (PD) is a common neurodegenerative disorder that afflicts approximately 1% of the population aged 60 or older.1 Patients diagnosed with PD often present with symptoms such as bradykinesia, resting tremor, and cogwheel rigidity, which typically persist and worsen over time. Levodopa combined with carbidopa is…
Engineering Medicine Featured Abstracts Neuroscience

Moving Past the Transplant: How Various Stem Cell Therapy Strategies are Complementing, Challenging, and Enhancing the Field of Cardiomyocyte Remuscularization after Heart Failure

June 22, 2023 Jordan Newman
Jordan Newman Background: Heart failure (HF) is the world’s leading cause of death1 and the most common diagnosis for hospital admissions over the age of 65 in developed countries.2 The permanent nature of cardiomyocytes renders cell death from HF a permanent cellular outcome with no cure. As a result, efforts…
Cardiology Featured Abstracts Stem Cells

Interpretable Machine Learning Models in Clinical Decision Support Systems

June 22, 2023 Gayatri Prakash
Gayatri Prakash Introduction: Machine learning is broadly defined as a subset of AI that utilizes algorithms to learn from data and make predictions/decisions.1 It has recently started to be incorporated into clinical decision support systems which are used to assist providers in making informed decisions about patient care.2 However even…
Artificial Intelligence Engineering Medicine Featured Abstracts

Anti-VEGF Therapies as Potential Treatment Option for Arteriovenous Malformations

June 22, 2023 Christopher Chaftari
Christopher Chaftari Background:  Arteriovenous malformations (AVM) are characterized by an abnormal connection between an artery and a vein, bypassing a capillary bed; this leads to a high velocity, low resistance flow which may cause serious complications like stroke, brain abscess and hemorrhage.1,2,3 Current treatment options include surgical interventions aimed to…
Cardiology Engineering Medicine Featured Abstracts

Advancements in GD2-CAR T Cell Therapy for Treatment-Resistant Gliomas: Current Progress and Future Perspectives

June 22, 2023 Robert Mbilinyi
Robert Mbilinyi, MS. and Vytas Bankaitis, Ph.D. Introduction: Gliomas, a diverse group of tumors originating from glial cells in the central nervous system (CNS), are the most common type of CNS tumors1,2. They include astrocytomas, oligodendrogliomas, and glioblastomas, with glioblastomas being the most dangerous, accounting for over 70-75% of CNS…
Cancer Featured Abstracts Immunology

The Role of Histone 3 Mutations as a Driving Force of Diffuse Intrinsic Pontine Glioma (DIPG) and its Molecular Targeting with Therapeutics

June 22, 2023 Zoë Cook
Zoë Cook Background:  Diffuse Intrinsic Pontine Glioma (DIPG) is a universally lethal and highly aggressive pediatric brainstem tumor located in the pons.1 DIPG is a rare condition, with only 200-300 cases per year in the United States, with average time of survival after diagnosis being ~9 months.8 Due to its…
Cancer Featured Abstracts