The Neuroadaptations from Prenatal Exposure to Opioids on Reward Pathway Receptors and the Implications for Vulnerability to Substance Use Disorders in the Future

Natalie Philipello Background: The opioid epidemic refers to the widespread and escalating crisis of opioid misuse and addiction, particularly in women of reproductive age1. It encompasses the overuse, abuse, and dependence on prescription opioids, heroin, and synthetic opioids, leading to devastating consequences including overdose deaths, increased healthcare costs, and prenatal…
Psychiatry

Exercise Improves Depression Through Interleukin-6

Hobad Huy Nguyen Background: Depression is a mental health disorder that affects 300 million people worldwide1 and is characterized by persistent impaired motivation, decreased mood, and in severe cases suicidality.2 According to the Diagnostic and Statistical Manual Version 5, Major Depressive Disorder (MDD) lasts for at least two weeks and…
Endocrinology Psychiatry

The Use of Music Therapy in Children with ASD and its benefits in Social Communication and Language Deficits

Claire Heigl Maza Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by a lack of social communication and use of restricted, repetitive behaviors. 2 Children with ASD often suffer from speech and language delays including difficulty in recognizing emotions from verbal stimuli. While treatments and interventions used in…
Featured Abstracts Psychiatry

Micro-RNA Mediated Regulation of the FKBP5 Gene Alters the HPA Axis in Response to Stress: Utility as a Biomarker to Improve PTSD Diagnosis

Olivia Lennon Background: Post-traumatic stress disorder (PTSD) is a chronic psychiatric disorder that can develop after exposure to a traumatic event or stressor.1 Approximately 10% of trauma-exposed individuals will develop PTSD.1,2 Certain groups have higher prevalence such as combat veterans and victims of rape with rates up to 20% and…
Psychiatry

The Role of EEG Mu Rhythm as a Potential Biomarker in Autism Spectrum Disorder

Aliehs Lee Background: Autism spectrum disorder (ASD) is a complex neurological condition marked by deficits in executive functioning, motor repetitions, and social interaction4. While the etiology of autism spectrum disorder remains unclear, research into potential biomarkers holds promise for improving early diagnosis and intervention3,4. The primary therapeutic approach for ASD…
Featured Abstracts Psychiatry

Autism and Epilepsy: Could UBE3A be the Genetic Link?

Kathryn Kuczkowski Background: Autism Spectrum Disorders (ASD) are developmental disorders characterized by variable levels of social skills, impaired communication, and repetitive behaviors. It’s estimated that epilepsy co-occurs in 15% of individuals diagnosed with ASD.¹ One genetic mechanism being evaluated in linking ASD and epilepsy is maternal overexpression of chromosome 15q11-q13 known…
Featured Abstracts Psychiatry

The Use of Music Therapy in Children with ASD and its benefits in Social Communication and Language Deficits

Claire Heigl Maza Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by a lack of social communication and use of restricted, repetitive behaviors. 2 Children with ASD often suffer from speech and language delays including difficulty in recognizing emotions from verbal stimuli. While treatments and interventions used in…
Featured Abstracts Psychiatry

Prenatal Cannabis Exposure Alters Endocannabinoid Brain Circuitry Leading to Adverse Psychiatric Consequences in Children

Laurel Foster Background: Prenatal cannabis exposure (PCE) is an increasingly relevant concern due to growing acceptance, legalization, and decriminalization of cannabis. As societal attitudes delineate marijuana as a “harmless” drug and women seek relief from morning sickness, nausea, vomiting, and anxiety, cannabis use during pregnancy has consequently increased in the…
Featured Abstracts Psychiatry