Kirby James Taylor Introduction. Type 1 diabetes mellitus (T1D) is a heterogeneous disorder effecting 1 and 300 Americans characterized by the destruction of pancreatic beta cells, resulting in an insulin deficiency [1]. Beta cells with immune infiltration from CD4+ T […]
Rishabh Shah Introduction. Diabetes mellitus is the most common metabolic disease related to impaired wound-healing conditions.1 2-3% will develop a diabetic foot ulcer (DFU) each year, and 15% will develop a foot ulcer during their lifetime.2 Even with extensive treatment, […]
Pouriska Kivanany Introduction. Diabetes is characterized by elevated blood glucose levels, decreased blood circulation, and reduced immune response.1, 2 Diabetic foot ulcers are the primary complication with diabetes and are responsible for 84% of diabetic lower leg amputations.3 In normal wound healing, […]
Kevin Chin Introduction: Worldwide, the prevalence of obesity has been steadily increasing over the past few decades. According to the World Health Organization (WHO), obesity worldwide has tripled since 1975. Defined as a Body Mass Index (BMI) of over 30, this […]
Ather Adnan Introduction: Type 1 Diabetes (T1D) is a complex autoimmune disease characterized by T-cell driven destruction of pancreatic β-cells in the islets of Langerhans and resultant hyperglycemia1. The pathogenesis of T1D involves presentation of normally cryptic β-cell autoantigens and […]
Allyson Jones Introduction: Postpartum depression, which effects as many as 30% of mothers, impairs mother-infant interactions and can have a profound effect on both child development and motherhood.1 Oxytocin is a key regulatory hormone that is known to buffer stress […]
Donald Hubbard II Introduction. Type I diabetes (T1DM) is an autoimmune disease due to destruction of pancreatic beta cells and results in hyperglycemia and hypoinsulinemia.1 It most often develops before the age of 30.2 The major causes of mortality in […]
Siin Park Introduction. Danger of obesity lies in secondary pathogenesis, and Type II Diabetes (T2D) is a predominant, consequential issue.1 T2D is marked by insufficient insulin production; obesity is an energy imbalance, leading to chronic oxidative stress and overactivated mitochondrial […]
Rishi Suresh Introduction. Ischemic stroke is a condition in which the brain is abruptly deprived of oxygen, leading to functional deficits. Epidemiologic studies have shown that young women experience strokes less frequently than similarly aged men; however, this trend reverses […]
William Shank Introduction. Type I diabetes mellitus (T1D) is a chronic disease characterized by autoimmune destruction of pancreatic β-cells leading to chronic insufficient insulin production. Lymphocytic infiltration and destruction of these cells, along with circulating islet cell antibodies and anti-insulin […]