Mast Cell Inhibitors as a Potential Target for Mitigation of Food Allergies

Shrey Patel Background: There are approximately 33 million Americans currently living with food allergies (FA), defined by their characteristic exaggerated immune responses to certain food allergens1.These unwanted allergic reactions may lead to severe life-threatening medical emergencies such as anaphylactic shock2. To prevent the immune response from progressing further, therapies such…
Engineering Medicine Featured Abstracts Immunology

Capsular Contracture: An Immunological Balancing Act

Afridi Abdullah Background: Capsular contracture (CC) is a common complication following breast implant surgery, marked by the abnormal thickening of fibrotic tissue around the implant. Specifically, there is an incidence of 10.6% across all implants.1 This condition leads to aesthetic changes, discomfort, and pain, impacting patient satisfaction and requiring surgical…
Engineering Medicine Featured Abstracts Fibrosis Immunology

Food for a Better Mood: Diet as a Modulator of the Gut Microbiome for the Treatment of Depression

Raiyan Talukder Background: Depression is one of the most common mood disorders in the world, characterized by at least 2 weeks of depressed mood, anhedonia, loss of interest, and other symptoms.1 Unfortunately, depression is a growing issue, affecting over 280 million people worldwide with some communities observing a large uptick…
Engineering Medicine Featured Abstracts Microbiology Psychiatry

Examining Helicobacter Pylori Pathogenesis and Motility Mechanisms

Anita Sumali Background: Helicobacter pylori (H. pylori) is one of the most prevalent human pathogens worldwide, infecting approximately half of the global population1. Its association with numerous gastrointestinal disorders, including gastritis, peptic ulcers, and gastric cancer highlights the urgent need for a thorough understanding of its pathogenesis mechanisms2. While extensive…
Engineering Medicine Featured Abstracts Microbiology

Bacteriophage Therapy as a Means of Resolving Biofilm Formation On Vascular Prostheses

Veronica Stuckey Background:  Vascular graft infections (VGIs) present an uncommon (1-3%) but potentially deadly (mortality 20-30%) post-surgical adverse effect. VGIs are biofilm associated infections resistant to antibiotic treatment due to difficulty penetrating the biofilm microenvironment[1]. Patients within the first 4 months post-operatively are at the highest risk of infections from…
Cardiology Engineering Medicine Featured Abstracts Microbiology

The Therapeutic Potential of Musical Training in Pediatric Patients with Attention-Deficit Hyperactivity Disorder

Kathleen Stephenson Background: The increasing prevalence of Attention Deficit Hyperactivity Disorder (ADHD) in the United States presents a multifaceted challenge, affecting approximately 11% of children and spurring an increase in demand for stimulant medications1. National shortages, along with growing parental apprehension regarding the long-term effects of prescription stimulant use in…
Engineering Medicine Featured Abstracts Psychiatry

Adeno-associated Vectors (AAVs) as a Genetic Therapy for Individuals with Duchenne Muscular Dystrophy

Magdalyn Snyder Background: Duchenne muscular dystrophy (DMD) results from a frameshift or nonsense mutation in the DMD gene found on the X chromosome, which encodes dystrophin (a 427-kDa cytoskeletal protein). Dystrophin plays a crucial role in skeletal and cardiac muscle and individuals with DMD experience progressive muscle weakness resulting in…
Engineering Medicine Featured Abstracts Neuroscience

A Current Understanding of Myocardial Recovery in the Treatment of Dilated Cardiomyopathy

Q. Smith Background: Dilated Cardiomyopathy (DCM) significantly reduces life expectancy and quality of life, with 1-year and 5-year survival rates of 70%-75% and 50%, respectively[1]. Remodeling of the left ventricle (LV) is central to DCM, driven by cardiomyocyte breakdown and pro-inflammatory pathways[2]. Treatment can slow or reverse tissue remodeling[3, 4,…
Cardiology Engineering Medicine Featured Abstracts