Home Featured Abstracts Mechanisms Regulating Th17 T Cells Implicated in the Pathogenesis of Autoimmune Conditions Like ArthritisTargeted Chemical Modification of BACE-1 Inhibitors: One Step Closer to the Prevention of Alzheimer’s DiseaseThe Role of Gut Microbiome Dysbiosis in Alzheimer DiseaseThe Use of Anesthetic Agents for Non-Anesthetic Purposes: Ketamine as an Alternative for Treatment-Resistant DepressionTissue Transglutaminase 2 (TG2) Post-Translational Modification of the Angiotensin II Receptor (AT1R) Plays a Role in the Pathogenesis of Essential HypertensionTargeting the Indoleamine 2,3-Dioxygenase Pathway to Suppress Pancreatic Ductal Adenocarcinoma MetastasisThe Epigenetic Role of MicroRNA’s in Retinoblastoma Proliferation and Invasion through Targeting of the Wnt/Beta-Catenin PathwayLin28/let-7 Axis Plays A Key role in Regulating Aerobic Glycolysis and Cancer Progression in Hepatocellular Carcinoma via PDK1MYC Promotion of Oxidative Phosphorylation Enhances Chemotherapy Resistance in Triple-Negative Breast CancerAssessing Endotypes of Asthma Including IL-33 and IRAK-1 (IL-R-Associated Kinase)Mechanisms of DNA Damage in Breast Cancer and Inhibition of DNA Repair through PARP InhibitorsMiR-34a Suppresses p53-Mediated Tumorigenesis and Epithelial-Mesenchymal Transition in Non-Small Cell Lung CancerDiabetic Wound Healing: New Targets and ApproachesHerpes simplex virus type 1 contributes to Alzheimer’s disease by preventing regulation of formation and destruction of Aβ amyloid plaques.SDHAP3 Epigenetic Alterations in Fetuses Exposed to Maternal Smoking and Other Neurodevelopmental DisordersMSC-Induced T-reg proliferation as a potential therapy for Multiple SclerosisIFN-γ/IDO Axis in the Mesenchymal Stem Cell Suppression of T-cells in Systemic Lupus ErythematosusEpigenomic-Based Diagnostic Techniques and Therapeutic Strategies for Ovarian CancerPropionic Acid as an Environmental Trigger and Treatment Target for Autism Spectrum DisorderAngiogenesis as a Treatment Avenue for Anaplastic Thyroid CarcinomaThe Role of Transforming Growth Factor-β in Tumor MetastasisEstrogen Receptor Beta Activation as a means of improving ischemic stroke outcomes in post-menopausal womenN-acetyl Cysteine and Rapamycin for the Treatment of SLE via Modulation of the Cellular Response to Reactive Oxygen SpeciesSulforaphane in Skin Cancer Prevention: mechanisms of action and potential in vivo limitationsThe Role of Mitochondria in Promoting Dysfunctional Neutrophil Extracellular Traps in Systemic Lupus Erythematosus PathogenesisThe impact of dysfunctional Parkin and PINK-1 on mitochondrial quality control in the pathogenesis of Parkinson’s DiseaseRole of the hyaluronic acid receptor, CD44, in resistance of ovarian cancer to chemotherapyLong Non-coding RNAs (lncRNAs) such as MALAT-1 Disrupt Regulatory Cell Mechanisms in the Pathogenesis of Ovarian Cancer.The Role of the HIF-1 Complex in Aerobic Glycolysis of Glioblastoma Multiforme (GBM)Mesenchymal stem cells (MSC) immunomodulation in Type I Diabetes MellitusInhibiting the PD-1/PD-L1 Interaction as an Intratumoral Immunotherapeutic Approach for MelanomaThe Controversial Theories of the Unfolded Protein Response and Autophagy as Underlying Mechanisms for the Increase in the Proinflammatory Cytokine IL-23 in Ankylosing Spondylitis.Role of maternal prenatal stress in dysregulation of the fetal Hypothalamic-Pituitary-Adrenal Axis, predisposing offspring to neurobehavioral disorders and depression.The Role of O-GlcNAcylation on G6PD in the Pentose Phosphate Pathway on Tumor Growth of Lung Cancers.Epigenetic Mechanism of DNA Methylation in Fetal Alcohol SyndromeThe Role of Immunity in Maintaining the Muscle Satellite Cell Niche Necessary for Satellite Cell Function in Health and in Duchenne Muscular DystrophyOverexpression of transcription factors Mafa and Pdx1 induces in-vivo transdifferentiation of pancreatic α cells to β-like insulin-producing cellsUsing Pro-Insulin Peptide Immunotherapy to Elicit a Foxp3 T-regulatory Response and Suppress Autoimmunity in Type 1 Diabetes MellitusRole of STAT5 in pathogenesis of Philadelphia chromosome positive Chronic Myelogenous Leukemia (CML)Obesity-associated Leptin Activation of Cancer Stem Cell Signaling in Triple Negative Breast Cancer
