Category: Orthopedics

Role of Surgical Technique in Outcomes after Meniscal Repair

July 28, 2025 Carson Benner
Carson Benner Background: The meniscus consists of two semilunar structures in the knee joint responsible for shock absorption and cartilage protection.1 Many ordinary and athletic activities can produce excessive rotational or shear forces that damage these structures, making meniscal tears are a common orthopedic injury. The incidence of meniscal tears…
Engineering Medicine Featured Abstracts Orthopedics

DKK1 as a Therapeutic Target for Osteolytic Bone Lesions

July 22, 2025 Jordan Myers
Jordan Myers Background: Osteolytic bone lesions are seen in a majority of patients with various forms of bone cancer and bone metastasis, with over 65% of Multiple Myeloma (MM) patients having pathologic fractures secondary to osteolytic bone lesions at some point in the course of their disease.1 Osteolytic bone lesions…
Orthopedics

Innovations in Anterior Cruciate Ligament Reconstruction Methods: Internal Bracing

June 25, 2024 Nathan Harward
Nathan Harward Background: The anterior cruciate ligament (ACL) is the chief ligament within the knee joint, responsible for anterior and rotational stability1. Most ACL ruptures are sports-related, and ligament reconstruction is generally preferred over attempted repair, even if the tear is partial2. Approximately 200,000 ACL reconstructions (ACLR) are performed each…
Engineering Medicine Featured Abstracts Orthopedics

Addressing the Rotator Cuff Problem: Lessons from the Hamstring

June 24, 2024 Andrei Demkov
Andrei Demkov Background: Rotator cuff (RC) injuries are prevalent among orthopedic pathologies, significantly contributing to the surgical burden each year.1 These injuries exhibit a spectrum of severity from minor partial-thickness tears to extensive, retracted disruptions. Typically addressed through arthroscopic techniques, the recurrence of tears post-repair varies widely; smaller tears exhibit…
Engineering Medicine Featured Abstracts Orthopedics

The Positive Molecular Impacts of Exercise on Vascular Endothelial Growth Factor (VEGF) and Bone Angiogenesis in the Non-Pharmacological Treatment/Prevention of Osteoporosis

June 12, 2024 Leo Toussaint
Leo Toussaint Background: Osteoporosis (OP) is a skeletal disease involving the degeneration of bone structure, strength, and density resulting in an increased risk of fractures.1 OP affects over 12% of US adults over 50 and causes over 2 million fractures with a cost of up to $17 million annually.2 Risk…
Featured Abstracts Orthopedics

A Non-Invasive Approach Utilizes YAP in Platelet-Derived Exosomes to Treat Tendon Injury

June 10, 2024 Connor Roper
Connor Roper Background: Tendons are constantly responsible for a proportionally high force load and are crucial to normal function1. Tendon injuries, including tendinitis and tendinopathy, can severely impact life quality and reportedly affect over 100 million people globally2. Mechanical overuse and age-related degeneration of tenocytes most often contribute to tendon…
Featured Abstracts Orthopedics

Inhibition of MicroRNA-141 and MicroRNA-145 as Potential Therapeutic Targets for Promoting Bone Mesenchymal Stem Cell Proliferation in Steroid-Induced Avascular Necrosis of the Femoral Head (SANFH)

June 5, 2024 Jason Noor
Jason Noor Background: Avascular necrosis of the femoral head is an orthopedic disease that occurs when the femoral head receives an inadequate supply of blood. This eventually leads to deterioration or collapse of the femoral head.1 The most common non-traumatic risk factor of avascular necrosis of the femoral head is…
Featured Abstracts Orthopedics