Sasha Burrowes Fetal Alcohol Syndrome (FAS) and Fetal Alcohol Spectrum Disorders (FASD) are leading non-genetic causes of neurodevelopmental disabilities in the US and worldwide1. Acting as a teratogen, ethanol has been shown to drastically change the developmental course of maturing […]
Syed Zamin Introduction. Osteoarthritis (OA) is a chronic condition due to the inflammation of synovium and breakdown of cartilage in joints which mainly affects the knees and hips1-2. It has a lifetime prevalence of 40% in males and 47% in […]
Eun Yoon Introduction. Cardiovascular diseases represent the leading cause of mortality in Western countries.1 Vascular endothelial injury may lead to the development of atherosclerosis. An immediate restoration of vascular endothelial lining is critical for the prevention of atherosclerotic vascular diseases.2,3 […]
Alesha White Introduction. Type 1 diabetes mellitus (T1DM) is an autoimmune condition that depletes b cell mass and insulin production thus rendering patients incapable of regulating glucose levels1-4. Patients often present with symptoms between the ages of 5 and 7 […]
Luke Villamaria Introduction. The Anterior Cruciate Ligament (ACL) is one of four major ligaments of the knee and plays an important role in stability of the knee upon movement. ACL rupture is a common sports injury with a prevalence estimated […]
Patrick Tansey Introduction: The long-bone fracture healing process requires a hematoma formation, callus formation, angiogenesis and remodeling of the bony-callus over years with osteoblast and osteoclast activity.1 Bone regeneration should occur spontaneously after initial intervention, however up to 10% of […]
Adam Olson Introduction. Damage to articular cartilage often results from physical trauma or age-related abrasion.4 In all cases, however, it leads to constant pain and functional limitations, and can predispose individuals to osteoarthritis.1,2,4 Once damaged, the poorly vascularized tissue is […]
Lan-Anh Nguyen Introduction. Acute respiratory distress syndrome (ARDS) is an acute form of diffuse lung injury occurring in patients with a predisposing risk factor, one of which being bacterial pneumonia induced by E. coli.1 While the incidence of nosocomial ARDS […]
Christopher Morin Introduction: Development of myocardial infarction (MI) occurs when a maturing plaque fissures and exposes its lipid rich core to components of circulating blood. The process ends with formation of an acute thrombus over the plaque with closure of […]
Megan Marcom Introduction: Alzheimer’s Disease (AD) is the most frequent type of dementia and neurodegeneration that occurs in middle to late life, and its prevalence is expected to double within 20 years as average lifespan increases.1 Pathologically, AD is characterized […]