Kevin Varghese Introduction. Ischemia is the blockage of arterial supply to live tissue, and prolonged ischemia leads to various types of tissue necrosis1,2, which occurs in response to the release of cytokines. Angiogenesis is a response to ischemia, which is […]
Kirby James Taylor Introduction. Type 1 diabetes mellitus (T1D) is a heterogeneous disorder effecting 1 and 300 Americans characterized by the destruction of pancreatic beta cells, resulting in an insulin deficiency [1]. Beta cells with immune infiltration from CD4+ T […]
Celina Garcia-Brinker Introduction. This literature review focuses on breast cancer and more specifically how controlling/reducing cancer stem cells (CSC) can provide beneficial effects including limiting epithelial-mesenchymal-transition (EMT), which allows for metastasis, as well as increasing chemo-sensitivity 1,5. Cancer stem cells […]
Timothy Deville Introduction. MSCs obtained from bone marrow, adipose tissue, and blood are important components of bone tissue engineering, because they have the potential for acting as progenitor cells and also have the capacity of self‐renewal1. In order to implant […]
Morgan Cattoor Introduction. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease driven by aberrant responses in both innate and adaptive immunity.1 Standard treatment consists of immunosuppressive agents such as corticosteroids, azathioprine, and methotrexate.2 When these therapies fail, mesenchymal stem […]
Megan Badejo Introduction. The Female Athlete Triad Syndrome has hallmark conditions of caloric/dietary deficiency, functional amenorrhea, and low bone mineral density (BMD)1. Focusing on the low bone mineral density condition, the syndrome affects female athletes in any sport at any […]
Hannakate Hall Introduction: Zika Virus is a positive sense, single stranded RNA flavivirus that has attracted worldwide attention within the last 5 years for its transcontinental spread and ability to evoke devastating results within certain patient populations1. Zika is transmitted […]
Rahul Ghosh Introduction: Low-back pain, commonly associated with age-related degenerative disc disease (DDD), is a major healthcare burden in the United States with an estimated 60% – 90% lifetime prevalence 1. Spinal fusion is the standard of treatment for advanced […]
William Shank Introduction. Type I diabetes mellitus (T1D) is a chronic disease characterized by autoimmune destruction of pancreatic β-cells leading to chronic insufficient insulin production. Lymphocytic infiltration and destruction of these cells, along with circulating islet cell antibodies and anti-insulin […]
Radhika Shah Introduction. Diabetes mellitus is a chronic disease in which the level of glucose in the blood cannot be maintained. Type I diabetes manifests as an autoimmune disorder, in which the patient’s immune system attacks the insulin-producing beta cells […]