Umbilical cord-derived mesenchymal stem cells are best suited for cartilage and bone regeneration

Ikanke-abasi James ¬†Introduction.¬† Sports injuries, accidental trauma, genetic defects, and aging are the most common causes of damage to articular cartilage and bony tissue. The incidence of hospitalized patient bone fractures is estimated to be 1 million in the United States. Surgery is the leading form of treatment. However, the risks associated with surgery include: […]

Hypoxia Induced Mesenchymal Stem Cells: The Treatment of Osteoarthritis

Michael Boyd Introduction: Osteoarthritis (OA) is a disease that arises from the deterioration or absence of cartilage in a joint. The resultant joint has 2 boney surfaces rubbing against one another, resulting in inefficient and painful movement for the patient1. The 2 bones then frequently undergo aberrant subchondral bone remodeling, making the problem worse. OA […]

Paracrine factors and mitochondrial transfer from mesenchymal stem cells ameliorate acute respiratory distress syndrome

Amanda Edinger Introduction: Acute respiratory distress syndrome (ARDS) is a lung condition characterized by bilateral lung infiltrates that results in hypoxia. ARDS can be secondary to a variety of disease processes or direct lung damage, however, the disease is characterized by diffuse alveolar damage leading to inefficient oxygen exchange between at the alveolar-capillary interface. Throughout […]