Modulator Therapy of F508 deletion in the Cystic Fibrosis Transmembrane Conductance Regulator
Drew Irion Background: Cystic Fibrosis is a hereditary ion channel mutation that results in chronic upper respiratory infections and intestinal blockage1. This condition impacts upwards of 30,000 people in the United States and approximately 60,000 people worldwide3,4. The most common form of cystic fibrosis, delta F508, is a deletion of…