Yoga as a Supplemental Therapy for Pediatric Cystic Fibrosis Patients

Swarali Panse Background: Cystic fibrosis (CF) is a genetic disorder primarily affecting respiratory function. Conventional physiotherapy and pharmacologic treatments are used in standard CF management, however, interest in complementary therapies like yoga are on the rise. Yoga, known for enhancing respiratory capacity and reducing stress, can potentially be used to…
Engineering Medicine Featured Abstracts Respiratory

Mesenchymal Stem Cells (MSCs) and MSC-Derivatives for Improving Outcomes with Sepsis-Induced Acute Respiratory Distress Syndrome

Ivan Rodriguez-Oliveros Background: Acute Respiratory Distress Syndrome (ARDS) is characterized by alveolar capillary damage that leads to inflammation and pulmonary edema.1 The tissue injury causes a decrease in lung compliance, requiring patients to be mechanically ventilated. Approximately 23% of all ventilated patients are those with ARDS.1 ARDS, classified through the…
Engineering Medicine Featured Abstracts Respiratory Stem Cells

Neonatal Respiratory Distress Syndrome Management in Resource-Limited Settings

Anika Kamisetty Background:  Neonatal respiratory distress syndrome (RDS) is one of the leading causes of morbidity and mortality for premature infants in low-income and middle-income countries (LMICs)1,6. RDS is due to deficiency in surfactant formation in premature lungs and is responsible for around 45% of preterm newborn deaths in some…
Engineering Medicine Featured Abstracts Respiratory

Anti-Ro52 Autoantibodies’ Role in Autoimmune Disorders, Inflammatory Myopathies, and Interstitial Lung Disease

Ashleigh Little Background: Autoimmune connective tissue diseases (CTDs) are disorders characterized by the immune system attacking the body’s tissues. These diseases can affect various organs and systems, leading to various clinical manifestations. This research specifically analyzed mixed connective tissue disease (MCTD), polymyositis/dermatomyositis (PM/DM), and systemic sclerosis (SSc). Objectives: This review…
Featured Abstracts Immunology Inflammation Respiratory

Inhibition of PDE4 and PI3Kδ in Addition to Stimulation of Nuclear Hormone Receptor PPAR in Emphysema Caused By Smoking

Haani Tai Introduction. Smoking-related emphysema induces a disruption to many cellular signaling pathways especially related to inflammation. With inhibition of Phosphoinositide 3-kinase δ (PI3Kδ) showing promising results for reducing inflammation as well as agonizing peroxisome proliferator-activated receptor γ (PPARγ) to induce an anti-inflammatory response and prevent a proinflammatory response.1 Methods. Two…
Engineering Medicine Respiratory

Mesenchymal Stem Cells as a Treatment for Acute Respiratory Distress Syndrome

Michael Biskup Introduction. Acute Respiratory Distress Syndrome (ARDS) is an inflammatory reaction of the lungs to cellular damage. ARDS commonly develops after trauma, infection, pleuritis, and aspiration. Hypoxemic respiratory failure is a defining characteristic. In the beginning stages of ARDS, the body releases inflammatory mediators such as IL-1. Neutrophils then…
Engineering Medicine Respiratory Stem Cells

Exploration of Novel Anti-Quorum Sensing Compounds in Pseudomonas Aeruginosa Inhabited Cystic Fibrosis Patients

Karan Hooda Introduction. Cystic Fibrosis (CF) is a genetic disorder in which there is a deletion of F508 in the cystic fibrosis transmembrane conductance regulator gene (CFTR).1 This leads to mucus buildup and dehydration of respiratory airway surfaces, providing the optimal environment for pathogens to inhabit.2 Pseudomonas aeruginosa is a…
Microbiology Respiratory