Category: Wound Healing

Composite and Engineered Reconstruction Methods for Severe Burn Wounds

July 29, 2026 Andrea Noy
Andrea Noy Background: Severe burn wounds accounted for nearly 13 million cases globally in 2021, and their prevalence is projected to increase. Recovery from such wounds is a multi-faceted and strenuous journey, requiring surgical intervention, skin grafting, physical therapy, and psychological rehabilitation. As such, the functionality and aesthetics following a…
Engineering Medicine Featured Abstracts Wound Healing

Bioelectronic Systems for Advanced Wound Management: Integrating Monitoring, Direct Therapy, and Closed-Loop Control

July 16, 2026 Maansi Srinivasan
Maansi Srinivasan Background.  Chronic wounds represent a global health burden, affecting 1-2% of the population, including up to 40% of hospital beds in settings[1]. In the United States alone, approximately 8.5 million individuals are affected, with annual treatment costs exceeding $28 billion [1,2].  While most acute wounds follow a well-orchestrated…
Engineering Medicine Featured Abstracts Wound Healing

Stem Cells and Skin Regeneration in Burn Wounds

July 17, 2025 Cason Dudney
Cason Dudney Background:  Burn wounds represent a significant clinical challenge due to their complexity, high morbidity, and long-term disability. Traditional therapies often fall short in addressing the extensive tissue loss and impaired healing in severe burns. Recent advances in regenerative medicine have highlighted the potential of stem cell-based therapies in…
Stem Cells Wound Healing

Using Deferoxamine to Improve Soft Tissue Regeneration following Achilles Tendon Repair

August 12, 2021 Steven Maxwell
Will Singer Introduction. The Achilles tendon is the strongest tendon in the body and facilitates walking, running, and jumping movements.1 Despite its strength, the incidence of Achilles tear has reached approximately 8.3 ruptures per 100,000 people over the last several years due to increased participation in recreational activities.2 Surgical management…
Featured Abstracts Orthopedics Wound Healing

The Use of Bioprinted Skin Grafts for Burn Wound Healing

August 6, 2021 Kavya Yeruva 
Kavya Yeruva  Introduction: Burns are one of the most common types of trauma, resulting in damage to the epidermis, dermis, and occasionally underlying tissue. The resulting pro-inflammatory response is initiated by vasodilation of nearby blood vessels and diapedesis of various cells into the injured area.1,2,3 Macrophages then release cytokines like…
Wound Healing

The Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles (MSC-EVs) in Promoting M2 Macrophage Polarization in Severe Cutaneous Burn Wounds Following MSC Treatment

July 29, 2021 Ian T. Bui
Ian T. Bui Introduction. Severe cutaneous burn wound is classified as a third- or higher-degree full thickness burn that involves destruction of epidermis and dermis1. Macrophages influence all steps in wound healing through their phenotypic polarization: pro-inflammatory M1 phenotype and anti-inflammatory M2 phenotype2,3. Traditional treatments such as Early Excision and…
Stem Cells Wound Healing