Targeting METTL3 Mediated m6A Methylation: A Novel Approach to Improving the Efficacy of Glioblastoma Multiforme Treatment
Janah Dia Background: Glioblastoma multiforme (GBM), a WHO grade IV glioma, is the most common and aggressive primary brain tumor in adults. It is characterized by poor prognosis and high resistance rate to aggressive multimodal therapy. Standard therapy protocol involves maximal surgical resection followed by radiation and temozolomide (TMZ) chemotherapy.…