Month: August 2025

Advancements in Alzheimer’s Disease Detection and Treatment

August 21, 2025 Adithya Shastri
Adithya Shastri Background: Alzheimer’s disease (AD) is a chronic, progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes. It currently affects over 6 million Americans and is a leading cause of disability in older adults13. Diagnosis often occurs late, after significant neuronal damage, which limits the effectiveness…
Engineering Medicine Featured Abstracts Neuroscience

The Role of Selective Dopamine D2 Agonists in Promoting Cardiomyocyte Recovery in Oxidative Stress-induced Peripartum Cardiomyopathy

August 12, 2025 Ayesha Sayyed
Ayesha Sayyed Background: Peripartum cardiomyopathy (PPCM), the most common dilated cardiomyopathy affecting previously heart-healthy women during late-term pregnancy, occurs due to left ventricular (LV) systolic dysfunction.1 Factors such as increased maternal age, multifetal pregnancies, pre-eclampsia, hypertension, tocolytic usage, and obesity, increase the risk of PPCM.2-5 PPCM is underdiagnosed due to…
Cardiology Featured Abstracts

Revolutionizing Parkinson’s Disease Treatment: Focused Ultrasound for Non-Invasive Gene Delivery Across the Blood-Brain Barrier

August 12, 2025 Nini Phan
Nini Phan Background: Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder worldwide, characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation of misfolded α-synuclein protein in Lewy bodies.1 PD is a progressively debilitating condition, marked by the cardinal symptoms…
Featured Abstracts Neuroscience

What Can Be Done to Structurally or Biologically Support the Apophysis of the Tibia in Children Who Suffer from Osgood-Schlatter Disease So That They May Continue Activity During Their Childhood?

August 7, 2025 Boyang Zhang
Boyang Zhang Background: Osgood-Schlatter Disease (OSD) is an activity and growth-associated knee pathology affecting the tibial tuberosity apophysis in adolescents. Up to 10% of adolescents are affected by OSD during their lifetime, often bilaterally.1 While treatment is generally conservative, there is significant variation in patient presentation and symptoms. Usually, patients…
Engineering Medicine Featured Abstracts

A Review of the Limitations and Future Directions of Kyphoplasty for Symptomatic Vertebral Compression Fractures

August 7, 2025 Jake Tinsley
Jake Tinsley Background: Vertebral compression fractures (VCFs) are among the most prevalent spinal injuries, especially in elderly patients and those with osteoporosis, malignancy, or trauma, with an estimated 1 in 4 women 50 years of age and older having experienced at least one VCF.1,2,3 VCFs occur when an axial force…
Engineering Medicine Featured Abstracts

Food for Thought: Exploring Dietary Influence on the Gut-Brain Axis and its Implications for Neuropsychiatric Disorders

August 5, 2025 Jacquelin Stanberry
Jacquelin Stanberry Background: Neuropsychiatric disorders with behavioral disturbances have been associated with gastrointestinal symptoms and altered gut microbiomes1. The gut-brain axis is a bidirectional communication network with implications for health and disease that operates through three main pathways: immune, endocrine/systemic, and neuronal2. The immune pathway communicates using inflammatory molecules, while…
Engineering Medicine Featured Abstracts Psychiatry

Investigating the Viral, Genomic, and Immunological Etiology of Type 1 Diabetes Mellitus

August 5, 2025 Anaarthi Srinivas
Anaarthi Srinivas Background: Type 1 Diabetes Mellitus (T1DM) is an autoimmune disease in which T-cells attack and destroy the insulin-producing cells of the pancreas1. As of 2021, 304,000 children and adolescents (those younger than 20) in the US had diagnosed T1DM; additionally, 5.7% of all adults with diabetes had T1DM3.…
Diabetes Engineering Medicine Featured Abstracts

Computational Methods for Early Detection of Diabetic Retinopathy

August 5, 2025 Shivani Sista
Shivani Sista Background: Diabetic retinopathy (DR) is a microangiopathy of the retina resulting from chronic hyperglycemia.1 It is the leading cause of blindness in the working-age population, and the fifth leading cause of preventable blindness worldwide.1,2 DR is characterized by progressive capillary damage and retinal ischemia, and advanced stages are…
Diabetes Engineering Medicine Featured Abstracts

S100A1 as a Therapeutic Peptide Target for Heart Failure

August 5, 2025 Keerthana Prayaga
Keerthana Prayaga Background: Heart failure is a significant health problem in the United States affecting over 6.5 million US adults1. Many newly introduced therapeutics have not been successful past preclinical trials and survival rates have stagnated despite existing therapies1,2. Failing cardiomyocytes are characterized by decreased cardiac performance, arrhythmias, tissue necrosis,…
Cardiology Featured Abstracts

ALDH2 Deficiency in Alcohol-Associated Hepatocellular Carcinoma: Mechanisms and Potential Drug Therapy

August 5, 2025 Evan Zuo
Evan Zuo Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, primarily due to its poor prognosis and ineffective diagnosis due to nonspecific symptoms early on.1,5,9 One of the primary drivers for HCC is chronic alcohol consumption.1,5,6 Alcohol is normally metabolized to acetaldehyde, a carcinogen whose subsequent…
Cancer Featured Abstracts