PI3K/AKT Pathway Drug Targets to Overcome EGFR-TKI Resistance in Lung Cancer
Danica Amirtham Background: Lung cancer remains one of the leading causes of cancer mortality worldwide, largely due to the lack of effective early screening, delayed onset of symptoms, and heterogeneity of tumors.1,2 Majority of the lung cancer cases are non-small cell lung cancer (NSCLC), and typically derived from mutations in…