Faraz Damghani Introduction. The suprachiasmatic nucleus controls the circadian rhythm of the body and disruptions of this rhythm has been linked to breast cancers. Breast cancer accounts for 25% of cancers which affect women, making it the most common malignancy […]
Ryan Kwong Introduction: The role of microRNAs (miRs) in cancer is just budding and has only been studied for the past 20 years. MiRs are short, non-coding single stranded RNA sequences that regulate other RNA transcripts and have been implicated […]
Tejaswini Reddy Introduction: Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults and the current standard of treatment of care is surgical resection of tumor(s) followed by external beam irradiation and taking cytotoxic agent temozolomide orally [1-6]. […]
Nishah Panchani Introduction: Approximately 12.4% of women will develop breast cancer during their lifetime[1]. Furthermore, 70% of all breast cancers are known to be caused by increased receptor-estrogen interaction (ER+)[2]. Studies have hypothesized that the proliferation promoting estrogen is produced […]
Yi-Hsien Yeh Introduction. Cancer cells evade immune cell recognition via expressing receptor such as PD-L1 on cell surface1,2. Agents activating immune defense and overcoming immunosuppression have been shown as promising immunotherapeutic strategies against drug resistant cancers, such as melanoma3. For […]
Andrew Trinh Introduction. Melanoma is a form of skin cancer that arises due to uncontrolled growth of melanocytes1 and is currently the fifth leading type of cancer in the world. Particularly in the past decade, the incidence of melanoma has […]
Kirk Tran Introduction. Colorectal cancer (CRC) is the third most common cause of cancer-related mortalities worldwide1. The pathogenesis of CRC is a multifactorial progression with accumulating genetic mutations and changes in expression levels of microRNAs2. While studies have shown microRNA-21 […]
Matthew Tjahja Introduction: Breast cancer is the most common cancer in the United States representing nearly 14.6% of all new cancer cases2. Melatonin is both an output and modulator/regulator of the central circadian clock. Several circadian clock genes such as […]
Spurthi Tarugu Introduction. Melanoma is a deadly form of skin cancer that occurs when melanocytes become cancerous. In early stages, the 5-year survival rate is over 98%; metastasis reduces it to 17%– making melanoma the deadliest type of skin cancer1. […]
P. Ryan Tacon Introduction: Glioblastoma multiforme (GBM) is an aggressive central nervous system tumor, often developing as a primary tumor from de novo mutations. GBM is the most common, and most life-threatening of brain tumors seen in practice, and treatment […]