PAD4’s Implications in the Pathogenesis and Treatment of Rheumatoid Arthritis

Morgan Lilly Background: Rheumatoid arthritis (RA) is an autoimmune disorder marked by joint inflammation, pain, stiffness, and damage.¹ Its origins are multifactorial, with over 100 genetic variations contributing to disease susceptibility, resulting in diverse pathogenic mechanisms.² RA is categorized into seropositive and seronegative subtypes, with the presence of anti-citrullinated protein…
Arthritis Engineering Medicine Featured Abstracts

Exploring Molecular Targets for Rheumatoid Arthritis Therapy

Purvi Desai Background: Rheumatoid arthritis (RA) affects around 1 % of the global population and causes chronic inflammation in joints, eventually leading to bone and cartilage damage. Early symptoms include joint swelling, tenderness, and fatigue, while overall systemic inflammation can damage various organs [1,2]. Inflammation is mediated by cytokines which…
Arthritis Engineering Medicine Featured Abstracts