HIF Axis Effects in Acute Mountain Sickness: Implications for Individual Susceptibility and Interventions
Kaleb Barker Background: An individual’s response after rapid ascent to high altitude (HA) depends on external factors (ascent rate, metabolic demands, environmental factors) and the individual’s physiology (genetics, underlying etiologies, hydration, nutrition)1,2. Given this multifaceted etiology, predicting an individual’s response to HA prior to ascent remains challenging1. Quantifying susceptibility to…