Chikungunya Virus: Pathogenesis of Persistent Arthralgia and Chronic Joint Disease
Brendan Mueller Introduction. Chikungunya disease is an acute-febrile illness, caused by the Chikungunya virus (CHIKV), which is debilitating, arthritic, and transmitted by mosquitoes in the genus Aedes1. Within the past 15 years, there has been a re-emergence of CHIKV outbreaks in temperate regions, as opposed to tropical regions in which…