Early life exposure to soy affects breast cancer susceptibility through regulation of ER and cytokines

Bailey King  Introduction. Breast cancer is the most common non-cutaneous cancer in women in the US.  Studies have found significant differences in the microbial composition between breast cancer patients and non-breast cancer patients.1 The diet affects breast cancer risk through multiple mechanisms, including estrogen and cytokines. Estrogens influence mammary gland…
Cancer Nutrition

Polyphenols Epigenetic Effects on Skin Cancer Prevention

Trang Tran Introduction. Skin cancer is the leading cancer diagnosed each year in the US.1,5 It has taken a toll on US economy costing $8.1 billion dollars in the US for skin cancer treatment.1,5 There is a number of risk factors that increasing one’s susceptibility for skin cancer: phenotypic markers…
Cancer Nutrition

The Role of a Western Diet in Regulating Expression of Farnesoid X Receptor and Colorectal Cancer Progression

Shaili Tapiavala Introduction. Colorectal cancer is the third most common cancer in the Western world (1,4).  Today, colorectal cancer patients have an improving prognosis due to early detection, but colorectal cancer is still the third-leading cause of cancer-related deaths in America (1,4).  Colorectal cancer has been correlated with a high…
Cancer Nutrition

Genetic Variants of Complement Factor H and a High-Fat Diet are Associated with the Pathogenesis of Age-Related Macular Degeneration

Jasmine Nguyen Introduction. Age-related macular degeneration (AMD) is the leading cause of visual deficit in older populations in the developed world.1   There are two different types of AMD: a wet type and a dry type. The wet type is characterized by exudate with choroidal neovascularization while the dry type is…
Neuroscience Nutrition

Mediterranean Diet’s Effects on Cancer and Epigenetics

Helen Chen Introduction.  Mediterranean diet meets the suggested dietary guidelines for Americans to increase overall health outcomes, and adherence to this diet has been associated with a decrease in 10% risk in overall cancer mortality.1,2 However, the specific mechanisms for how this diet causes a decrease in inflammation and cancer…
Cancer Nutrition