Category: Psychiatry

Adjunctive Treatment of Neurosteroids Sequesters Drug-Resistant Behavioral Seizures in Children with CDKL5 Deficiency Disorder

September 26, 2024 Michael Neff
Michael Neff Background: Cyclin-dependent like kinase 5 (CDKL5) Deficiency Disorder is an X-linked mutation that leads to severe developmental delays, spontaneous seizures, and early death in infants.6,7,8 CDKL5 is a serine threonine kinase that is a key regulator of early neuronal development that controls the aggregation of glutamatergic receptors, GABA-A…
Featured Abstracts Psychiatry

Food for a Better Mood: Diet as a Modulator of the Gut Microbiome for the Treatment of Depression

June 28, 2024 Raiyan Talukder
Raiyan Talukder Background: Depression is one of the most common mood disorders in the world, characterized by at least 2 weeks of depressed mood, anhedonia, loss of interest, and other symptoms.1 Unfortunately, depression is a growing issue, affecting over 280 million people worldwide with some communities observing a large uptick…
Engineering Medicine Featured Abstracts Microbiology Psychiatry

The Therapeutic Potential of Musical Training in Pediatric Patients with Attention-Deficit Hyperactivity Disorder

June 28, 2024 Kathleen Stephenson
Kathleen Stephenson Background: The increasing prevalence of Attention Deficit Hyperactivity Disorder (ADHD) in the United States presents a multifaceted challenge, affecting approximately 11% of children and spurring an increase in demand for stimulant medications1. National shortages, along with growing parental apprehension regarding the long-term effects of prescription stimulant use in…
Engineering Medicine Featured Abstracts Psychiatry

The Neuroadaptations from Prenatal Exposure to Opioids on Reward Pathway Receptors and the Implications for Vulnerability to Substance Use Disorders in the Future

June 10, 2024 Natalie Philipello
Natalie Philipello Background: The opioid epidemic refers to the widespread and escalating crisis of opioid misuse and addiction, particularly in women of reproductive age1. It encompasses the overuse, abuse, and dependence on prescription opioids, heroin, and synthetic opioids, leading to devastating consequences including overdose deaths, increased healthcare costs, and prenatal…
Psychiatry

Exercise Improves Depression Through Interleukin-6

June 5, 2024 Hobad Huy Nguyen
Hobad Huy Nguyen Background: Depression is a mental health disorder that affects 300 million people worldwide1 and is characterized by persistent impaired motivation, decreased mood, and in severe cases suicidality.2 According to the Diagnostic and Statistical Manual Version 5, Major Depressive Disorder (MDD) lasts for at least two weeks and…
Endocrinology Psychiatry

The Use of Music Therapy in Children with ASD and its benefits in Social Communication and Language Deficits

May 31, 2024 Claire Heigl Maza
Claire Heigl Maza Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by a lack of social communication and use of restricted, repetitive behaviors. 2 Children with ASD often suffer from speech and language delays including difficulty in recognizing emotions from verbal stimuli. While treatments and interventions used in…
Featured Abstracts Psychiatry

Micro-RNA Mediated Regulation of the FKBP5 Gene Alters the HPA Axis in Response to Stress: Utility as a Biomarker to Improve PTSD Diagnosis

May 31, 2024 Olivia Lennon
Olivia Lennon Background: Post-traumatic stress disorder (PTSD) is a chronic psychiatric disorder that can develop after exposure to a traumatic event or stressor.1 Approximately 10% of trauma-exposed individuals will develop PTSD.1,2 Certain groups have higher prevalence such as combat veterans and victims of rape with rates up to 20% and…
Psychiatry

The Role of EEG Mu Rhythm as a Potential Biomarker in Autism Spectrum Disorder

May 31, 2024 Aliehs Lee
Aliehs Lee Background: Autism spectrum disorder (ASD) is a complex neurological condition marked by deficits in executive functioning, motor repetitions, and social interaction4. While the etiology of autism spectrum disorder remains unclear, research into potential biomarkers holds promise for improving early diagnosis and intervention3,4. The primary therapeutic approach for ASD…
Featured Abstracts Psychiatry

Autism and Epilepsy: Could UBE3A be the Genetic Link?

May 31, 2024 Kathryn Kuczkowski
Kathryn Kuczkowski Background: Autism Spectrum Disorders (ASD) are developmental disorders characterized by variable levels of social skills, impaired communication, and repetitive behaviors. It’s estimated that epilepsy co-occurs in 15% of individuals diagnosed with ASD.¹ One genetic mechanism being evaluated in linking ASD and epilepsy is maternal overexpression of chromosome 15q11-q13 known…
Featured Abstracts Psychiatry