Category: Stem Cells

Neurogenesis in Neurodegenerative Disease- The Possibility of Neural Stem Cells in Alzheimer’s Treatment

October 4, 2017 Megan Marcom
Megan Marcom  Introduction: Alzheimer’s Disease (AD) is the most frequent type of dementia and neurodegeneration that occurs in middle to late life, and its prevalence is expected to double within 20 years as average lifespan increases.1 Pathologically, AD is characterized by widespread synaptic and neuronal loss, inflammation, and two hallmark…
Neuroscience Stem Cells

Redox Preconditioning Promotes the Survival of Cardiac Stem Cells Under Oxidative Stress After Transplantation

October 4, 2017 Melanie Kwan
Melanie Kwan Introduction: Survival of cardiac stem cells (CSCs) after transplantation is necessary to facilitate cardiac repair following damage to the heart due to their potential ability to regenerate cardiomyocytes. The current best estimate of post-transplantation survival of CSCs is only approximately 10%.1 The primary cause of transplanted CSC death…
Cardiology Stem Cells

Mesenchymal Stem Cells in Cardiac Repair

September 21, 2017 Javier Benitez
Javier Benitez Introduction: Myocardial Infarction (MI) is a major public health problem that results in cardiac remodeling and resulting impaired heart function. Current treatment aims to prevent maladaptive pathways, but not seek to compensate for the loss of myocardium1. The use of Mesenchymal Stem Cells (MSCs) has proven to be…
Cardiology Stem Cells

Paracrine factors and mitochondrial transfer from mesenchymal stem cells ameliorate acute respiratory distress syndrome

September 5, 2017 Amanda Edinger
Amanda Edinger Introduction: Acute respiratory distress syndrome (ARDS) is a lung condition characterized by bilateral lung infiltrates that results in hypoxia. ARDS can be secondary to a variety of disease processes or direct lung damage, however, the disease is characterized by diffuse alveolar damage leading to inefficient oxygen exchange between…
Respiratory Stem Cells