Month: July 2017

The Use of Bone Marrow-Derived Mesenchymal Stem Cells to Aid in Tendon-Bone Healing Post-Anterior Cruciate Ligament Surgical Repair

July 31, 2017 Zachary Grant
Zachary Grant Introduction. Anterior Cruciate Ligament (ACL) tears have an incidence of between 36.9 and 60.9 per 100,000 persons/year, resulting in approximately 200,000 injuries annually.5 They most commonly occur in athletes involved in sports that require contact and/or sharp, sudden movements.2 The current method of repair involves surgically removing the…
Featured Abstracts Orthopedics

Multidrug Resistant Pseudomonas aeruginosa: Targeting essential genes as a novel therapy for healthcare-associated pneumonia

July 31, 2017 Julie England
Julie England Introduction: Pseudomonas aeruginosa is a major cause of healthcare- and ventilator-associated pneumonia (HAP, VAP). This complication produces significant increases in mortality, morbidity, and cost of care.1,2 20% of Pseudomonas pneumonia cases are caused by multidrug resistant (MDR) strains.3 Importantly, the presence of an MDR strain is the most…
Featured Abstracts Microbiology

The Role of Astrocyte Dysfunction in the Pathogenesis of Epilepsy

July 31, 2017 Kieran Boochoon
Kieran Boochoon Introduction: Astrocytes are a subtype of glial cell that have important functions maintaining ion concentrations, water transport, and neurotransmitter levels during neuronal activity.1 Recent studies have implicated that astrocytes could an important role in the pathogenesis of epilepsy. Different processes such as astrocytic Kir channels2, aquaporin channels3, gap…
Featured Abstracts Neuroscience

Intestinal Microbiome & Autism: exploring the contribution of specific microbiome differences (like Clostridium, Bacteroides, Prevotella, and Sutterella species) in autism-spectrum disorder children on symptomology

July 31, 2017 Puja Panwar
Puja Panwar Introduction. Compared to neurotypical controls, autism spectrum disorders (ASD) children more commonly experience hospitalizations with complaints of diarrhea, chronic constipation, and abdominal pain1. Several studies have shown abnormal gut microbiota in children with ASD. Studies using the maternal immune activation (MIA) model look at the offspring of MIA…
Featured Abstracts Microbiology Neuroscience

High Intensity Interval Training as Treatment for Type 2 Diabetes Mellitus

July 31, 2017 Alex Gustafson
Alex Gustafson Introduction: Type 2 Diabetes Mellitus (T2D) is a chronic disease characterized by insulin resistance, systemic inflammation, and impaired GLUT-4 translocation1. T2D has become epidemic in the U.S. as 1/3 of the population is diabetic or pre-diabetic2. These Americans are susceptible to major hyperglycemic related consequences such as strokes,…
Endocrinology Featured Abstracts

A gut feeling: the influence of intestinal microbiota by-products in autism spectrum disorders

July 31, 2017 Ankita Brahmaroutu
Ankita Brahmaroutu Introduction. Autism spectrum disorders (ASDs) are a range of pervasive neurodevelopmental disorders, with autism at the center of the spectrum. ASDs include impairments in social interaction, communication, restricted interests, and repetitive behavior with no definitive etiology. Children with autism are more than twice as likely to develop gastrointestinal…
Featured Abstracts Microbiology Neuroscience

Ang-2 and VEGF Inhibition alters tumor associated macrophages and normalizes tumor vasculature in glioblastoma

July 31, 2017 Tejaswini Reddy
Tejaswini Reddy  Introduction: Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults and the current standard of treatment of care is surgical resection of tumor(s) followed by external beam irradiation and taking cytotoxic agent temozolomide orally [1-6]. However, many tumors develop resistance to temozolomide, which is why…
Cancer Featured Abstracts

Inflammation and stress in preeclampsia due to microparticles of the endothelium and the trophoblast

July 31, 2017 Laura Chahin
Laura Chahin Introduction – The maternal condition preeclampsia currently has an incidence of 3-5%1 and affects both neonates and mothers globally as the most common cause of mortality2. Preeclampsia can be identified beginning at 20 weeks gestation by hypertension, protein present in urine, and, most concerning, damage to additional organs1.…
Featured Abstracts Reproduction