Category: Pregnancy

Targeting AT1-AA Signaling: A Novel Therapeutic Approach to Reduce Maternal Hypertension and Systemic Complications in Preeclampsia

July 3, 2026 Morgan Sheppard
Morgan Sheppard Background: Preeclampsia is a multisystemic condition which develops after 20 weeks of gestation.1,2 It is identified as new onset hypertension and is frequently accompanies with systemic complications such as proteinuria, eclampsia, acute kidney injury, hepatic injury, and fetal growth restriction.1,2 Preeclampsia is considered the most common cause of…
Pregnancy

The Role of Gut Microbiota-Derived Metabolites in the Pathogenesis and Clinical Translation of Preeclampsia

July 3, 2026 Prathi Selvapathi
Prathi Selvapathi Background: Preeclampsia is a hypertensive disorder of pregnancy associated with maternal endothelial dysfunction, placental abnormalities, fetal growth restriction, and increased maternal-fetal morbidity and mortality. Although current management strategies primarily focus on symptom control and delivery, disease-modifying therapies remain limited. Recent studies have demonstrated that gut microbiota composition is…
Featured Abstracts Microbiome Pregnancy

Role of MALAT1 and PGIF As Potential Biomarkers for Pre-Eclampsia

July 1, 2026 Sameera Dabbiru
Sameera Dabbiru Background: Pre-eclampsia is a systemic condition of hypertension and proteinuria during pregnancy that primarily involves placental dysfunction.1 A diagnosis requires a recurrent blood pressure greater than 140/90 mmHg and greater than 300 mg proteinuria sample.2,3 The disease is characterized by limited placenta perfusion due to damaged spiral arteries…
Pregnancy