Evaluating Genomic Methods for Assessing Fecal Microbiota Transplant (FMT) Efficacy After Antibiotic Use

Abhinaya Muruganandham Background.  Fecal microbiota transplantation (FMT) is a transformative therapy for restoring gut microbial ecology, particularly in treating recurrent Clostridioides difficile infection (rCDI) [1,2,3,4]. While highly successful for rCDI, its efficacy varies in other conditions like inflammatory bowel disease (IBD) or antibiotic-associated diarrhea [4]. Antibiotics significantly disrupt intestinal ecology,…
Engineering Medicine Featured Abstracts Microbiome

The Role of Demodex folliculorum Density in Modulating the Cutaneous Microbiome and Inflammatory Pathways in Rosacea

Sion Jung Background: Rosacea is a chronic inflammatory skin disorder characterized by erythema, flushing, vasodilation, inflammatory papules, and ocular symptoms such as dryness and photophobia [1]. The pathogenesis of rosacea remains unclear, with UV exposure, genetic predisposition, and environmental triggers implicated [1]. Emerging evidence highlights alterations in the skin microbiome,…
Engineering Medicine Featured Abstracts Inflammation Microbiome

The Role of Gut Microbiota-Derived Metabolites in the Pathogenesis and Clinical Translation of Preeclampsia

Prathi Selvapathi Background: Preeclampsia is a hypertensive disorder of pregnancy associated with maternal endothelial dysfunction, placental abnormalities, fetal growth restriction, and increased maternal-fetal morbidity and mortality. Although current management strategies primarily focus on symptom control and delivery, disease-modifying therapies remain limited. Recent studies have demonstrated that gut microbiota composition is…
Featured Abstracts Microbiome Pregnancy

Targeting Colorectal Cancer Prevention Through the Gut Microbiome

Arianette Campos Background: Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, and increasing incidence among younger adults highlights the need for improved prevention strategies Although localized disease is often treatable, many tumor-promoting mechanisms occur before symptoms become clinically apparent. The gut microbiome has emerged as an…
Cancer Microbiome

Assessing the Effects of Space Travel on the Gut Microbiome and the Potential Impacts on Future Mission Planning

Anokhi Kholwadwala  Background: Compared to Earth, those living aboard the ISS are exposed to reduced microbial diversity and higher concentrations of synthetic chemicals1. Astronauts exposed to this environment experience increased gut permeability wherein substances from the gut leak into the bloodstream causing issues like inflammation2. The presence of microgravity is…
Engineering Medicine Featured Abstracts Microbiome