Targeting Adipogenic Pathways for Osteoporosis Treatment: Combined Therapies as a Strategy for Disease Reversal
Samantha Hopper Background: Osteoporosis (OP) is a progressive skeletal disorder defined by a reduction in bone mineral density (BMD), diagnosed by a T-score ≤-2.5 via dual-energy x-ray absorptiometry.¹ This decline in BMD stems from a disruption in the balance between osteoblast-mediated bone formation and osteoclast-driven resorption, a process often influenced by…