Category: Osteoporosis

Spinal Cord Injury (SCI): Biological Interventions Shifting Cell Signaling to Prevent Osteoporosis and Promote Repair

July 3, 2026 Samuel Tran
Samuel Tran Background: Spinal cord injury (SCI) leads to rapid deterioration of cortical and cancellous bone below the lesion site, creating significant risk for fractures and limiting rehabilitative options such as weight-bearing exercises and exoskeleton use. ¹ Skeletal deterioration reflects an imbalance between osteoblast and osteoclast function, mainly at the…
Neuroscience Osteoporosis

Targeting Adipogenic Pathways for Osteoporosis Treatment: Combined Therapies as a Strategy for Disease Reversal

July 17, 2025 Samantha Hopper
Samantha Hopper Background: Osteoporosis (OP) is a progressive skeletal disorder defined by a reduction in bone mineral density (BMD), diagnosed by a T-score ≤-2.5 via dual-energy x-ray absorptiometry.¹ This decline in BMD stems from a disruption in the balance between osteoblast-mediated bone formation and osteoclast-driven resorption, a process often influenced by…
Osteoporosis